Renal disease associated to the metabolic syndrome

  • Alejandro Spagnolo Servicio de Nefrología y Hemodiálisis, Clínica San Nicolás, Buenos Aires
  • Emilio Puccio Servicio de Nefrología y Hemodiálisis, Clínica San Nicolás, Buenos Aires
  • Alfredo Spagnolo Servicio de Nefrología y Hemodiálisis, Clínica San Nicolás, Buenos Aires
Keywords: metabolic syndrome, insulin resistance, nephropathy, cardiovascular risk

Abstract

The metabolic syndrome is a common disorder that results from the increasing prevalence of obesity and the pathophysiology seems to be attributable to insulin resistance. This condition is related to glomerular sclerosis and renal failure through several mechanisms, including environmental factors, sympathetic overactivity, stimulation of the Renin-Angiotensin-Aldosterone System and a proinflammatory state.
The increased risk for type 2 Diabetes and cardiovascular disease demands therapeutic attention for those at high risk. The main approach is weight reduction and increased physical activity.

 

How to cite this article:

Spagnolo A, Puccio E, Spagnolo A. Renal disease associated to the metabolic syndrome. Rev Nefrol Dial Traspl. 2009;29(4):169-72.

Published
2009-08-28
How to Cite
1.
Spagnolo A, Puccio E, Spagnolo A. Renal disease associated to the metabolic syndrome. Rev Nefrol Dial Traspl. [Internet]. 2009Aug.28 [cited 2024May12];29(4):169-72. Available from: http://www.revistarenal.org.ar/index.php/rndt/article/view/348
Issue
Vol. 29 No. 4 (2009): Oct.-Dic.
Section
Review Article