Hiperuricemia, enfermedad renal crónica y trasplante renal (parte II)

Contenido principal del artículo

Liliana Miriam Obregón
Carlos Cobeñas
Carlos Díaz
Gabriela Greco
Rosana Groppa
Nora Imperiali
Hugo Sergio Petrone
Gervasio Soler Pujol
Marcelo Fabián Taylor
Alicia Ester Elbert

Resumen

La hiperuricemia (HU) en el trasplante renal (TR) ha sido definida igual que en la población general en las Guías KDIGO como valores por encima de 6 mg/dl en mujeres y 7 mg/dl en hombres. La incidencia de HU en algunas poblaciones es de 28%1, alcanzando el 80% en la era Ciclosporina (CSA)2. La HU se observa precozmente luego del TR, los factores de riesgo asociados con su desarrollo incluyen: edad avanzada al momento del TR; historia de gota o HU pre-existente; obesidad; presencia de síndrome metabólico (SM); deterioro de la función del injerto; uso de inmunosupresores, principalmente ciclosporina (CSA); uso de diuréticos.

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1.
Obregón LM, Cobeñas C, Díaz C, Greco G, Groppa R, Imperiali N, Petrone HS, Soler Pujol G, Taylor MF, Elbert AE. Hiperuricemia, enfermedad renal crónica y trasplante renal (parte II). Rev Nefrol Dial Traspl. [Internet]. 1 de junio de 2016 [citado 20 de octubre de 2021];36(2):124-36. Disponible en: http://www.revistarenal.org.ar/index.php/rndt/article/view/67
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