Manejo de la hiperuricemia en pacientes en Argentina. Una encuesta mediante cuestionario

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Guillermo A. De’Marziani
Teresa Bensusán
María Estela Canda
Yanina M. Castaño
Fabiana Davila
Guillermo Dieuzeide
Claudio Daniel González
Paula Iscoff
Yanina V. Maccio
Estrella Menéndez
Elisa Morales
Liliana Obregon
María J. Pomares
Jimena Soutelo
Fabiana P. Vázquez
Gloria Viñes
Alicia E. Elbert

Resumen

Introducción: Durante muchos años el ácido úrico se ha considerado como un producto metabólico inerte del metabolismo de las purinas, sin embargo, ha sido recientemente asociado a una serie de estados de enfermedad crónica. No hay hallazgos concluyentes disponibles en la actualidad para tomar una conducta activa clara respecto al tratamiento de ácido úrico sérico, y cuál sería su objetivo terapéutico. Material y métodos: Debido a esta controversia, se decidió llevar a cabo una encuesta para evaluar cuáles son las decisiones que se toman en este contexto, en el ámbito médico de la Argentina. Se consultó en qué pacientes se evaluaba en forma rutinaria el ácido úrico sérico, resultando en un 53.2% de todos los pacientes, sin diferenciar patologías, y un 11.5% refirió que no lo realiza rutinariamente. Con respecto al tratamiento sólo refirieron tratarlo con enfermedad renal un 62.5%; con diabetes 61.7%; con síndrome metabólico 60.4%; con enfermedad cardiovascular un 50.3%; con gota, cálculos renales o dolor articular, un 91.3%, 74% y 36.1% respectivamente. Resultados: Los datos de la encuesta confirman la falta de evidencia en el criterio para la selección de pacientes, a los fines de evaluar los niveles de ácido úrico sérico y su tratamiento. Conclusiones: De esta forma, se concluye que prima la necesidad de realizar estudios prospectivos y randomizados de las patologías con alta incidencia de uricemia elevada, para poder determinar normativas que orienten una conducta a los especialistas según los resultados obtenidos, y que dicha decisión no esté basada solo en la opinión de los expertos.

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1.
De’Marziani GA, Bensusán T, Canda ME, Castaño YM, Davila F, Dieuzeide G, González CD, Iscoff P, Maccio YV, Menéndez E, Morales E, Obregon L, Pomares MJ, Soutelo J, Vázquez FP, Viñes G, Elbert AE. Manejo de la hiperuricemia en pacientes en Argentina. Una encuesta mediante cuestionario. Rev Nefrol Dial Traspl. [Internet]. 19 de septiembre de 2019 [citado 20 de octubre de 2021];39(3):175-83. Disponible en: http://www.revistarenal.org.ar/index.php/rndt/article/view/462
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